Cancer usually begins with a genetic mutation in a single cell, resulting in unlimited proliferation and eventual metastasis to distant sites. In this process, in addition to cancer cells, microenvironmental support is also required, manifested by immune cells (including T cells, B cells, tumor-associated macrophages, natural killer cells, etc.), vascular endothelial cells, collagen cells, the joint effects of adipocytes, apoptotic cells, cell-free cancer DNA, exosome extracellular matrix, etc. They also require nutrient supply, acidic environment, and hypoxic environment.

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Almost all the cancer medications currently on the market are related to cancer cells, but no medications that improve the tumor microenvironment are available yet.

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As early as the 1960s, Chinese medicine practitioners discovered in their medical practice that killing cancer cells through simple chemotherapy, radiotherapy and other means could not improve the patient’s quality of life or prolong the patient’s life in many cases. However, using tonic traditional Chinese medicine, patients’ quality of life has been significantly improved and their life span has been significantly extended. Moreover, long-term treatment can control tumor growth and even shrink tumors. Research now suggests that these are at least partly related to improving the tumor microenvironment. The effect of traditional Chinese medicine on tumors has also changed the concept of tumor treatment. Now, to evaluate the efficacy of a treatment, tumor shrinkage is no longer the only indicator, but the extension of life expectancy is more important.

We believe that for cancer tissue, we need to not only attack it, but also surround its environment and cut off its resources to make it unsuitable for cancer to survive. Such a combination can minimize the off-target effects of chemotherapy and other treatments, making treatment more precise, peaceful and effective. This is the core concept of our siege therapy.